Drug interactions can alter how medications work or increase the risk of severe side effects. Taking Norpramin with some drugs causes serotonin syndrome, which is potentially fatal.
Some of the supplements or drugs that patients can’t take with desipramine due to toxicity include:
- Avoid taking imipramine medication since it works similar to Norpramin
- Herbal supplements like St. John’s wort increase the risk of serotonin syndrome
- Antidepressant medications like MAOIs and SSRIs
- Heartburn medications that contain acid blockers tamper with the body’s ability to process Norpramin
- Alcohol which causes dizziness and sedation
- Anticholinergics such as scopolamine, alkaloids, and atropine
- Blood pressure medication
- Thyroid supplements
- HIV protease inhibitors
Patients should disclose their medications before beginning treatment with Norpramin to avoid serotonin syndrome. Before taking decongestants, one should check the labels or check with their pharmacist. The drug can affect the effectiveness of desipramine.
Norpramin is an FDA-approved antidepressant that treats the symptoms of depression. The starting dosage for Norpramine is usually 25 mg, and it increases depending on how the patient responds to treatment. Although desipramine is less likely to cause adverse side effects, some common signs are blurred vision, dry mouth, dizziness, and bloating. Immediately contact the doctor if the situation gets worse.
Contact us at Mango Clinic for depression treatment options, or book your appointment today for more information on treating depression with Norpramin or another medication.