How Long Does Vyvanse Stay in Your System?

September 19, 2019


Attention Deficit Hyperactivity Disorder (ADHD) is a treatable medical condition that affects both adults and children. ADHD is diagnosed based on specific criteria that include a complete history and evaluation by a healthcare provider. Although most people were diagnosed with ADHD during their youth, it is possible for an adult not to be diagnosed until later in life. In this article, we will go back to discussing Vyvanse and its effects on one’s body.

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Despite some common misconceptions, children do not grow out of this disorder, symptoms change over time and what may have been an issue during their youth may not be once the patient has reached maturity. Although some individuals may not have been diagnosed until adulthood, the disorder was always present. It is believed that some children are capable of creating coping mechanisms and masking the telltale signs of ADHD. Once the demands of work and family life changed, what once worked to hide the symptoms no longer effective leading to frustration, confusion, and often anxiety. 

Although the symptoms of ADHD differ from person to person, common ones do exist. Listed below are just a few that are often seen in adults with this condition. 

ADHD Symptoms:

  • Makes careless mistakes and lacks attention to details
  • Often has difficulty paying attention to tasks
  • Seems not to listen when spoken to directly
  • Fails to follow through on instructions or duties in the workplace
  • Lack of organizational skills
  • Avoids participating in jobs that require sustained mental effort
  • Loses thing easily
  • Easily distracted by other things including unrelated thoughts
  • Forgetfulness
  • Restlessness 
  • Unable to participate in leisure activities
  • Excessive talking
  • Difficulty waiting on others
  • Often interrupts or intrudes on others

These symptoms can affect individuals at home, work, or in social situations. To be diagnosed, five or more of these symptoms must occur for at least six months and be present in two or more settings. Additionally, there must be clear evidence that the symptoms interfere with a person’s social or work functions and that they are not due to another mental health disorder. 




ADHD Medications

Since ADHD was first recognized as a separate mental health disorder, researchers have studied ways to help individuals cope. The two ADD/ADHD treatments that currently show the most benefit are therapy and medications. While therapy is often an excellent place to learn effective coping mechanisms, drugs have been developed that help patients function normally.

Vyvanse is a prescription medication that was developed to treat adults who have ADHD. It is designed to increase attention while decreasing impulsiveness. Approved in 2007 by the FDA, Vyvanse is a prodrug, and its side effects are considered to be less harsh than other ADHD medications. A prodrug is an inert substance that is metabolized in the body to become an active medication; in this case dextroamphetamine. Dextroamphetamine increases the availability of dopamine and norepinephrine in the central nervous system. These chemicals work together to maintain alertness, increase focus and sustain thought, effort, and motivation.

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How Long Does Vyvanse Take to Kick-In?

Vyvanse is a biologically inactive compound, meaning it must be taken orally and broken down by the body’s enzymes before it can be used. As a result, it typically takes one to two hours to take action and lasts for about 14 hours.


How Long Does 20, 30, 60, 70 mg Vyvanse Last?

Vyvanse comes in several dosages including 10, 20, 30, 60 and 70 mg. There may be a slight difference. The amount of time Vyvanse lasts in the body may vary depending on the dosage. However, in general, the active chemical (Dextroamphetamine) of the drug is cleared from the body in 20 hours.

How Long Does Vyvanse Stay in Breast Milk?

Breastfeeding outweighs the dangers of concurrent therapy with stimulants, the most widely prescribed drugs available in immediate-release and extended-release formulations, for the vast majority of lactating women with ADHD. Only a small percentage of ADHD individuals require medication that could make breastfeeding impossible. In such circumstances, the danger of the mother’s symptoms worsening if medication is withdrawn must be weighed against potential hazards to the infant if treatment is prolonged.


How Long Does Vyvanse Stay in Your Urine?

Drug tests are often used to screen for the presence of amphetamines. Not only can they detect the parent drug but the metabolites left behind as the drug is processed as well. Individuals who are prescribed certain medications should be aware that if their employer requires random drug screening, those who take Vyvanse will receive a positive test. Proper documentation such as a current prescription should be readily available if a drug screening is administered. 

Vyvanse is currently only available in an extended-release capsule. The effects of this medication will last from 10-14 hours after administration, but it can be screened for in the urine up to three days after usage even if a second dosage is not administered.

Some people may process Vyvanse faster than others depending on the rate their body metabolizes it. Also, younger, healthier, and even larger people tend to eliminate medications more quickly than others. Those who have health problems or organ function impairment excrete drugs slower.


Does Vyvanse Show Up on a Urine Test?

A urine test for vyvanse may not always show up. It can be spotted if the test is for amphetamines. This is due to the fact that it can identify the presence of the medication’s metabolites for a longer amount of time than blood.  The person getting tested can get their reports immediately because the results are instantaneous. Vyvanse’s oral dose radioactivity is measurable in urine for up to 120 hours, or 5 days.




Will Vyvanse Make You Fail a Drug Test?

The simple answer is YES! In this case, your rights are governed by state drug testing regulations as well as the federal Americans with Disabilities Act (ADA). In the end a positive drug test will almost certainly protect you from discipline or termination provided you have a doctor’s prescription to back it.


How Long Does Vyvanse Stay in Your Blood?

Blood screenings for  Vyvanse use have a relatively short detection window. Approximately eight hours after using this medication, a blood test will not indicate usage. In fact, the window is so short that Vyvanse is very rarely detected by this method. 

Medical practitioners often require drug screenings when prescribing amphetamines to their patients. This type of drug can be highly addictive and is often abused. To ensure that prescribing recommendations have been followed, routine testing may be ordered to verify the amount of Vyvanse in the patient’s system. Individuals who have been taking it as prescribed should not worry. However, if too much of this powerful drug is detected, your provider may discontinue its use. The FDA lists Vyvanse as a Schedule II class drug and is considered dangerous if not carefully monitored. 

If Vyvanse is used by someone who was not prescribed, they can experience side effects such as irritability, anxiety, and sleep disturbances. Rarely individuals, including those who have a prescription for its use, can have more severe complications such as panic attacks, hallucinations, mania, delusions, and paranoia. Be sure to discuss anything unusual with your mental health provider.

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What is Vyvanse Half-life?

A single dose medication is generally removed from the body after 5 half-lives. Given that Vyvanse has a half-life of less than an hour, its active ingredient, Lisdexamfetamine dimesylate, should be removed from the body in 4 to 5 hours following the previous dose.



If you think Vyvance might help you get in contact with Mango Clinic in Miami to schedule an appointment with one of their physicians specializing in helping ADHD patients.


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